The U.S. should attempt to focus upon areas that have environments better suited for our military than Afghanistan. We will not win the war there. However, Pakistan is such a threat that it demands our attention. Pakistan has nuclear weapons and the missile systems to deliver them. In order to keep this war from going nuclear we must contain Pakistan. Similar changes will need to occur in Pakistan as is necessary in the Middle East.
The war must be won in the Middle East. This is where Islam is the most aggressive and entrenched. This is the source of Islam and how it is interpreted. This is the epicenter of Islam and the change that MUST occur.
The large potential for warfare in Africa is one place to become more directly involved. This is a shooting war that is widespread. If we do not engage on a significant level of combat consistently, we will make it easier for the enemy to obtain WMD. By engaging in offensive combat, we will drain the enemy of valuable resources, in both material and manpower. The obvious targets of Syria and Iran should be the first to go. Ultimately, these governments will need to be changed. However, the West does not have the political will to begin a new conflict over these governments. In the meantime, we need other targets. While we probably lack the manpower for massive troops to be deployed, we should become more directly involved in the violence that is happening in Africa. Particular attention should be given to North Africa.